Disease: Metastatic non-small cell lung cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZEB1 P37275 zinc finger E-box binding homeobox 1 Transcription factor 0.97 0.442 0.808
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNFSF14 O43557 TNF superfamily member 14 Signaling 5.2E-02 0.529 0.769
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
THBS1 P07996 thrombospondin 1 1.00 0.407 0.885
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
SLC5A5 Q92911 solute carrier family 5 member 5 Transporter 2.9E-03 0.499 0.769
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
SELE P16581 selectin E 7.9E-10 0.447 0.808
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
PRDM14 Q9GZV8 PR/SET domain 14 1.9E-02 0.644 0.500
PKM P14618 pyruvate kinase M1/2 Kinase 0.85 0.482 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
PDCD1 Q15116 programmed cell death 1 0.42 0.402 0.846
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808